The full program will be made available shortly.
The first day is dedicated to perceptual learning, focusing on learned improvements in sensory discrimination and the underlying changes in neural signals and plasticity that occur at the cellular and circuit level. The lectures will cover: perceptual learning in the visual system (Roelfsema), texture discrimination in the whisker system of the mouse (Helmchen), the vestibular system and self-motion perception (Cullen), reciprocal relations between perceptual and motor learning during somatosensory discrimination and speech motor learning (Ostry), the probabilistic mathematical underpinnings of perceptual learning (Pouget), and developmental hereditary predisposition unveiled by large-scale twin research (Boomsma).
Pieter Roelfsema – Deep Learning in The Brain: the Role of Cortical Feedback Connections in Plasticity
Alexandre Pouget – Learning, Uncertainty and Confidence
Fritjof Helmchen – Mesoscale Brain Dynamics during a Sensory Discrimination Task
David Ostry – The Boundary between Motor and Perceptual Learning
Kathleen Cullen – The Rapid Updating of Internal Models of Voluntary Self-motion in the Primate Cerebellum: Implications for Perception and Action
Dorret Boomsma – Human Individual Differences: Twin and Genetic Association Studies
During our second day experts in the field of motor control and sensorimotor learning will discuss how motor actions are encoded and sequenced as well as how skilled movements are acquired and refined at the cellular, circuit and systems level. Lectures will cover: how motor skills can be defined (John Krakauer), prosthetic learning in the motor cortex (Daniel Huber), behavioral state modulation of associative learning (Megan Carey), circuit correlates for dexterity (Adam Hantman) and mechanisms underlying cerebellar motor memory formation (Tom Otis). A key note lecture by Rui Costa will follow at the end of the day in which the role of the basal ganglia in motor action sequencing will be highlighted.
Tom Otis – Cerebellar Circuit Mechanisms of Normal Movement & Ataxia
Megan Carey – Behavioural State Modulation of Associative Learning in Mouse Cerebellum
Adam Hantman – Neural Circuits of Dexterity
Daniel Huber – Cortical Circuit Dynamics during Neuroprosthetic Learning
John Krakauer – How Should we Think about Motor Skill?
Rui Costa – Generating and Shaping Novel Action Repertoires
PARTY @ Tolhuis
Dance the night away !
On our third and final day, we will focus on disease mechanisms affecting procedural learning. Specifically, we will focus on genetic, molecular and systems level disruptions that can lead to autism spectrum disorder and motor learning deficits. We will look at both the animal models and patients’ population exploring the etiology of those disorders and discussing potential treatment options.
Roy Sillitoe – Genetic Dissection of Cerebellar Inhibitory Interneuron Function
Sam Wang – The Cerebellum, Sensitive Periods, and Autism
Amy Bastian – Learning and Relearning Movement
Simon Fisher – Understanding the Impact of FOXP2 Gene Disruptions in Humans, Mice and Songbirds
YOUNG TALENT speakers
(Selected from Abstracts)